2018

Past Group Members

Emma Silvester

Emma completed her PhD in Andrew Turberfield’s Lab in the department of physics, studying the folding properties of DNA and RNA nanostructures. Following her PhD, she worked as a postdoc in the Division of Structural Biology in Kay Grünewald's lab, using DNA nanostructures to develop new tools for cryo-electron microscopy and tomography. In the Baldwin lab, Emma was using cryo-electron tomography to study the structural properties of membraneless organelles, formed by phase separation of intrinsically disordered proteins.

Mark Hickling

Mark's research is focussed on membraneless organelles and their ability to selectively enrich for certain RNA molecules.  He is investigating how the properties of the RNA and the proteins that constitute these structures affect this poorly understood selection process, and uses a combination of deep sequencing and bioinformatics to do so. Outside of research he is usually found either on the squash court or getting frustrated watching Arsenal play football! 

Charles Buchannan

Charlie works on biological NMR method development.  He is particularly interested in using NMR to unpick complex disease-relevant questions.  Recently he has developed a technique to extensively characterise pathogen-ligand interactions using Saturation Transfer Difference NMR, underpinned by previous work on NMR spectral deconvolution.  He is now focused on further applying spectral deconvolution to other experiments, aiming to expedite biological work with NMR.  Outside of research, Charlie competed in the Oxford-Cambridge Boat Race in 2019. After completing his PhD he was postdoc in the Baldwin lab for a year and is now postdoc in Marburg.

Gogulan Karunanithy

Gogs completed his undergraduate degree in Chemistry at the University of Oxford, spending his Part II year in the Baldwin Group. He has completed an EPSRC-funded DPhil in the group, and is interested in NMR methodology development. Publications

CONTACT INFORMATION:
gogulan.karunanithy AT keble.ox.ac.uk


Virginia Casablancas Antras

Virginia was a doctoral student with the Systems Approaches to Biomedical Science CDT, and is jointly supervised by collaborators at EliLilly. The main aim of her research is understanding the mechanisms of amyloid protein aggregation and inhibition using NMR and chemical kinetics approaches. She has also recently started working on the partitioning of small molecules into membraneless organelles. She is generally interested in studying biologically relevant phenomena at the protein interaction level, and in the combination of modelling and experimental approaches.  
Virginia’s background is in Biomedical Sciences (UAB, Spain, 2014) and she later completed an MRes in Molecular Biophysics at King’s College London, funded by a LaCaixa Fellowship for Postgraduate Studies in Europe. During her masters thesis in Prof. James McDonnell’s lab, she focused on the structural asymmetry and allostery of the immunoglobulin E constant region. After finishing her Dphil in group was working as a postdoc on the project about membraneless organelles, before starting a new role in the Nuffield Department of Medicine.
Outside the lab, Virginia plays the cello in the Oxford Millenium Orchestra, as well as being part of the Oxford University Table Tennis Team.

Satoshi Kishigami

Mr. Satoshi Kishigami was a Dphil student at the University of Oxford. His research projects focused on the development of novel chemical probes to investigate structures and dynamics of high molecular weight macromolecules, and mechanistic study for potential treatments against neurodegenerative diseases. His study at Oxford has been founded by Keidanren (Japan Business Federation) Ishizaka Memorial Foundation, Ezoe Memorial Recruit Foundation, Shigeta Foundation and Sakaguchi International Scholarship Foundation.
Satoshi holds BSc in Applied Chemistry from Keio University, Tokyo and he also studied synthetic organic chemistry at Rice University, Texas where he conducted a research project about the synthesis of anti-cancer natural product derivatives under the supervision of Prof K. C. Nicolaou.