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Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonal and functionally restricted.
Deimel LP, Myopie L, Sun G, Lewis V, Turner A, Buchanan CH, Burnap SA, Kutuzov M, Kobras CM, Demyanenko Y, Mohammed S, Stracy M, Struwe WB, Baldwin AJ, Naismith J, Davis BG, Sattentau QJ
Nature communications 14: 6851 (2024)
Link to open access publication
Deimel LP, Myopie L, Sun G, Lewis V, Turner A, Buchanan CH, Burnap SA, Kutuzov M, Kobras CM, Demyanenko Y, Mohammed S, Stracy M, Struwe WB, Baldwin AJ, Naismith J, Davis BG, Sattentau QJ
Nature communications 14: 6851 (2024)
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69
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Ion binding with charge inversion combined with screening modulates DEAD box helices phase transitions. Crabtree MD, Holland J, Pillai AS, Kompella PS, Babl L, Tuner NN, Eaton JT, Hochberg GKA, Arts DGAL, Redfield C, Baldwin AJ, Nott TJ. . Cell Reports 42 (11), (2023)
Link to open access publication
Link to open access publication
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Biocatalytic reductive lamination as a route to isotopically labelled amino acids suitable for analysis of larger protein by NMR
Rowbotham JS, Nicholson JH, Ramirez MA, Urata K, Todd PMT, Karunanithy G, Lauterbach L, Reeve HA, Baldwin AJ, Vincent KA
Chemical Science 14 12160, (2023)
Link to OA publication
Rowbotham JS, Nicholson JH, Ramirez MA, Urata K, Todd PMT, Karunanithy G, Lauterbach L, Reeve HA, Baldwin AJ, Vincent KA
Chemical Science 14 12160, (2023)
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67
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Uncovering the role of N-glycan occupancy on the cooperative assembly of Spike and Angiotensin converting enzyme 2 complexes insights from glycoengineering and native mass spectrometry
El-Baba TJ, Lutomski CA, Burnap S, Bolla J, Baker LA, Baldwin AJ, Struwe W, Robinson C
JACS 145 (14) 8021-8032 (2023)
Link to publication
El-Baba TJ, Lutomski CA, Burnap S, Bolla J, Baker LA, Baldwin AJ, Struwe W, Robinson C
JACS 145 (14) 8021-8032 (2023)
Link to publication
66
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Posttranslational, site-directed photochemical fluorine editing of protein side chains to probe residue oxidation state via 19F-nuclear magnetic resonance
Isenegger PG, Josephson B, Gaunt B, Davy MJ, Gouverneur V, Baldwin AJ, Davis B
Nature Protocols 18, 1543-1562 (2023)
Link to publication
Isenegger PG, Josephson B, Gaunt B, Davy MJ, Gouverneur V, Baldwin AJ, Davis B
Nature Protocols 18, 1543-1562 (2023)
Link to publication
65
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Efficiently computing the Uhlman fidelity for density matrices
Baldwin AJ, Jones J
Physical Review A 107 012427 (2023)
Link to publication
Baldwin AJ, Jones J
Physical Review A 107 012427 (2023)
Link to publication
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Pathogen-sugar interactions revealed by universal saturation transfer analysis
Buchanan, C.J., Gaunt, B., Harrison, P., Yang, Y., Liu, J., Khan, A., Giltrap, A.M., Le Bas, A., Ward, P.N., Gupta, K., Dumoux, M., Tan, T.K., Schimaski, L., Daga, S., Picchiotti, N., Baldassari, M., Benetti, E., Fallerini, C., Fava, F., Gilberto, A., Koukos, P.I., Davy, M.J., Lakshminarayanan, A., Xue, X., Papadakis, G., Deimel, L.P., Casablancas-Antras, V., Claridge, T.D.W., Bonvin, A.M.J.J., Sattentau, Q.J., Furrini, S., Gori, M., Huo, J., Owens, R.J., Schaffitzel, C., Berger, I., Renieri, A., Naismith, J.H., Baldwin, A.J., Davis, B.G.
Science 377 (6604) (2022)
Pre-publication on science
Buchanan, C.J., Gaunt, B., Harrison, P., Yang, Y., Liu, J., Khan, A., Giltrap, A.M., Le Bas, A., Ward, P.N., Gupta, K., Dumoux, M., Tan, T.K., Schimaski, L., Daga, S., Picchiotti, N., Baldassari, M., Benetti, E., Fallerini, C., Fava, F., Gilberto, A., Koukos, P.I., Davy, M.J., Lakshminarayanan, A., Xue, X., Papadakis, G., Deimel, L.P., Casablancas-Antras, V., Claridge, T.D.W., Bonvin, A.M.J.J., Sattentau, Q.J., Furrini, S., Gori, M., Huo, J., Owens, R.J., Schaffitzel, C., Berger, I., Renieri, A., Naismith, J.H., Baldwin, A.J., Davis, B.G.
Science 377 (6604) (2022)
Pre-publication on science
63
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Reductive site-selective atypical C,Z-type/N2-C2 cleavage allows C-terminal protein amidation
Mollner, T.A., Giltrap, A.M., Zeng, Y., Demyanenko, Y., Buchanan, C., Oehlrich, D., Baldwin, A.J., Anthony, D.C., Mohammed, S., Davis, B.G.
Science Advances 8 (14) (2022)
Mollner, T.A., Giltrap, A.M., Zeng, Y., Demyanenko, Y., Buchanan, C., Oehlrich, D., Baldwin, A.J., Anthony, D.C., Mohammed, S., Davis, B.G.
Science Advances 8 (14) (2022)
62
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Quantitative chemical exchange saturation transfer imaging of nuclear Overhauser effects in acute ischemic stroke
Msayib, Y., Harston, G.W.J., Ray, K.J., Larkin, J.R., Sutherland, B.A., Sheeran, F., Blockley, N.P., Odell, T.W., Jezzard, P., Baldwin, A., Simson, N.R., Kennedy, J., Chappell, M.
Magnetic Resonance in Medicine (2022)
Msayib, Y., Harston, G.W.J., Ray, K.J., Larkin, J.R., Sutherland, B.A., Sheeran, F., Blockley, N.P., Odell, T.W., Jezzard, P., Baldwin, A., Simson, N.R., Kennedy, J., Chappell, M.
Magnetic Resonance in Medicine (2022)
61
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Post-translational insertion of boron in proteins to probe and modulate function
Mollner, T.A., Isenegger, P.G., Josephson, B., Buchanan, C., Lercher, L., Oehlrich, D, Flemming Hansen D., Mohammed, S., Baldwin, A.J., Gouverneur, V., Davis, B.G.
Nature Chemical Biology 17 (2021)
Mollner, T.A., Isenegger, P.G., Josephson, B., Buchanan, C., Lercher, L., Oehlrich, D, Flemming Hansen D., Mohammed, S., Baldwin, A.J., Gouverneur, V., Davis, B.G.
Nature Chemical Biology 17 (2021)
60
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A weakened interface in the P182L variant of HSP27 associated with sever Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins
Alderson, T.R., Adriaenssens, E., Asselbergh, B., Pritisanac, I., Van Lent, J., Gastall, H.Y., Waelti, M.A., Louis, J.M., Timmermann, V., Baldwin, A.J., Benesch, J.L.P.
The EMBO journal 49 (8) (2021)
Link
Alderson, T.R., Adriaenssens, E., Asselbergh, B., Pritisanac, I., Van Lent, J., Gastall, H.Y., Waelti, M.A., Louis, J.M., Timmermann, V., Baldwin, A.J., Benesch, J.L.P.
The EMBO journal 49 (8) (2021)
Link
59
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Fast molecular compression by a hyper thermal collision gives bond-selective mechanochemistry
Krumbein, L., Anggara, K., Stella, M., Michnowicz, T., Ochner, H., Abb, S., Rinke, G., Portz, A., Duerr, M., Schlickum, U., Baldwin, A., Floris, A., Kern, K., Rauschenbach, S.
Physical Review Letters 126 (5) (2021)
Link
Krumbein, L., Anggara, K., Stella, M., Michnowicz, T., Ochner, H., Abb, S., Rinke, G., Portz, A., Duerr, M., Schlickum, U., Baldwin, A., Floris, A., Kern, K., Rauschenbach, S.
Physical Review Letters 126 (5) (2021)
Link
58
Filed in:Pre-print
Cryptic SARS-CoV2-spike-with-sugar interactions revealed by 'universal' saturation transfer analysis
Buchanan, C.J., Gaunt, B., Harrison, P.J., Le Bas, A., Khan, A., Giltrap, A.M., Ward, P.N., Dumoux, M., Daga, S., Picchiotti, N., Baldassarri, M., Benetti, E., Fallerini, C., Fava, F., Giliberti, A., Koukos, P.I., Lakshminarayanan, A., Xue, X., Papadakis, G., Deimel, L.P., Casablancas-Antras, V., Claridge, T.D.W., Bonvin, A.M.J.J., Sattentau, Q.J., Fuirai, S., Gori, M., Huo, J., Owens, R.J., Renieri, A., Naismith, J.H., Baldwin, A.J., Davis, B.G.
BioRxiv (2021)
Buchanan, C.J., Gaunt, B., Harrison, P.J., Le Bas, A., Khan, A., Giltrap, A.M., Ward, P.N., Dumoux, M., Daga, S., Picchiotti, N., Baldassarri, M., Benetti, E., Fallerini, C., Fava, F., Giliberti, A., Koukos, P.I., Lakshminarayanan, A., Xue, X., Papadakis, G., Deimel, L.P., Casablancas-Antras, V., Claridge, T.D.W., Bonvin, A.M.J.J., Sattentau, Q.J., Fuirai, S., Gori, M., Huo, J., Owens, R.J., Renieri, A., Naismith, J.H., Baldwin, A.J., Davis, B.G.
BioRxiv (2021)
57
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Cell-permable Ianthanide-platinum (IV) anti-cancer prodrugs
Yao, K. Karunanithy, G., Howarth, A., Holdship, P., Thompson, A.L., Christensen, K.E., Baldwin, A.J., Faulkner, S., Farrer, N.J.
Dalton Transactions 50(25) (2021)
Link
Yao, K. Karunanithy, G., Howarth, A., Holdship, P., Thompson, A.L., Christensen, K.E., Baldwin, A.J., Faulkner, S., Farrer, N.J.
Dalton Transactions 50(25) (2021)
Link
56
Filed in:Pre-print
aB-crystallin affects the morphology of AB (1-10) aggregates
Mueller, H., Dias, D.M., van der Zalm, A., Baldwin, A.J.
bioRxiv (2021)
Mueller, H., Dias, D.M., van der Zalm, A., Baldwin, A.J.
bioRxiv (2021)
55
Filed in:Pre-print
Repulsive electrostatic interactions modulate dense and dilute phase properties of bimolecular condensates
Crabtree, M.D., Holland, J.H., Kompella, P., Babl, L., Turner, N., Baldwin, A.J., Nott, T.J.
bioRxiv (2021)
Crabtree, M.D., Holland, J.H., Kompella, P., Babl, L., Turner, N., Baldwin, A.J., Nott, T.J.
bioRxiv (2021)
54
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Light-driven post-translational installation of reactive protein side chains
Josephson, B., Fehl, C., Isenegger, P.G., Nadal, S., Wright, T.H., Pop, A.W.J., Bower, B.J., Giltrap, A.M., Chen, L., Batchelor-McAuley, C., Roper, G., Arisa, O., Sap, J.B.I., Kawamura, A., Baldwin, A.J., Mohammed, S., Compton, R.G., Gouverneur, V., Davis, B.G.
Nature 585 (7826) 530-537 (2020)
Link
Josephson, B., Fehl, C., Isenegger, P.G., Nadal, S., Wright, T.H., Pop, A.W.J., Bower, B.J., Giltrap, A.M., Chen, L., Batchelor-McAuley, C., Roper, G., Arisa, O., Sap, J.B.I., Kawamura, A., Baldwin, A.J., Mohammed, S., Compton, R.G., Gouverneur, V., Davis, B.G.
Nature 585 (7826) 530-537 (2020)
Link
53
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Local frustration determines loop opening during catalytic cycle of an oxidoreductase
Stelzl, L.S., Mavridou, D.A., Saridakis, E., Gonzalez, D., Baldwin, A.J., Ferguson, S.J., Sansom, M.S.P., Redfield, C.
eLife 9 e54661 (2020)
Link
Stelzl, L.S., Mavridou, D.A., Saridakis, E., Gonzalez, D., Baldwin, A.J., Ferguson, S.J., Sansom, M.S.P., Redfield, C.
eLife 9 e54661 (2020)
Link
52
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Conditional disorder in small heat-shock proteins
Alderson, T.R., Ying, J., Bax, A., Benesch, J.L.P., Baldwin, A.J.
Journal of molecular biology 432 (9), 3033-3-49 (2020)
Link
Alderson, T.R., Ying, J., Bax, A., Benesch, J.L.P., Baldwin, A.J.
Journal of molecular biology 432 (9), 3033-3-49 (2020)
Link
51
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Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A
Juarez-Jimenez, J., Gupta, A.A., Karunanithy, G., Mey, A.S.J.S., Georgiou, C., Ioannidis, H., De Simone, A., Barlow, P.N., Hulme, A.N., Walkingshaw, M.D., Baldwin, A.J., Michel, J.
Chemical Science 11(10) 2021
Link
Juarez-Jimenez, J., Gupta, A.A., Karunanithy, G., Mey, A.S.J.S., Georgiou, C., Ioannidis, H., De Simone, A., Barlow, P.N., Hulme, A.N., Walkingshaw, M.D., Baldwin, A.J., Michel, J.
Chemical Science 11(10) 2021
Link
50
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An in-cell diffusion method to characterize the size, abundance and permeability of cells
Karunanithy G, Wheeler RJ, Tear L, Farrer NJ, Faulkner S, Baldwin AJ*
JMR 302 1-13 (2018)
INDIANA software: http://indiana.chem.ox.ac.uk/
Karunanithy G, Wheeler RJ, Tear L, Farrer NJ, Faulkner S, Baldwin AJ*
JMR 302 1-13 (2018)
INDIANA software: http://indiana.chem.ox.ac.uk/
49
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HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C
Collier, M., Alderson, T.R., de Villiers, C., Nicholls, D., Gastall, H., Allison, T., Degiacomi, M., Fuerst, D., van de Ven, P., Djinovic-Carugo, K., Baldwin, AJ, Watkins, H., Gehmlich, K., Benesch, J.L.P.
Science Advances 5 eeaav8421(2019)
Link
Collier, M., Alderson, T.R., de Villiers, C., Nicholls, D., Gastall, H., Allison, T., Degiacomi, M., Fuerst, D., van de Ven, P., Djinovic-Carugo, K., Baldwin, AJ, Watkins, H., Gehmlich, K., Benesch, J.L.P.
Science Advances 5 eeaav8421(2019)
Link
48
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Local unfolding of the HSP27 monomer regulates chaperone activity
Alderson TR, Roche J, Dias DM, Gastall HY, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ*
Nature communications, 10 1068 (2019)
Link
Alderson TR, Roche J, Dias DM, Gastall HY, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ*
Nature communications, 10 1068 (2019)
Link
47
Filed in:Pre-print
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
Wheeler, R.J., Lee, H.O., Poser, I., Pal, A., Doeleman, T., Kishigami, S., Kour, S., Anderson E.N., Marrone, L., Murthy, A.C., Jahnel, M., Zhang, X., Boczek, E., Fritsch, A., Fawzi, N.L., Sterneckert, J., Pandey, U., David, D.C., Davis, B.G., Baldwin, A.J., Hermann, A., Bickle, M., Alberti, S., Hyman, A.A.
bioRxiv
Wheeler, R.J., Lee, H.O., Poser, I., Pal, A., Doeleman, T., Kishigami, S., Kour, S., Anderson E.N., Marrone, L., Murthy, A.C., Jahnel, M., Zhang, X., Boczek, E., Fritsch, A., Fawzi, N.L., Sterneckert, J., Pandey, U., David, D.C., Davis, B.G., Baldwin, A.J., Hermann, A., Bickle, M., Alberti, S., Hyman, A.A.
bioRxiv
46
Filed in:Research Articles
Measuring Diffusion Constants of Invisible Protein Conformers by Triple Quantum 1H CPMG Relaxation Dispersion
Yuwen T, Sekhar A, Baldwin AJ, Vallurupalli P, Kay LE
Angewandte Chemie Int Ed. 57 51(2018)
link
Yuwen T, Sekhar A, Baldwin AJ, Vallurupalli P, Kay LE
Angewandte Chemie Int Ed. 57 51(2018)
link
45
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Formation of a translocation competent protein complex by a dynamic wrap-around binding mechanism
Gupta AA, Reinartz I, Karunanithy G, Spilotros A, Jonna VR, Hofer A, Svergun DI, Baldwin AJ, Schug A, Wolf-Watz M
JMB 14:430:3157-3169 (2018)
link
Gupta AA, Reinartz I, Karunanithy G, Spilotros A, Jonna VR, Hofer A, Svergun DI, Baldwin AJ, Schug A, Wolf-Watz M
JMB 14:430:3157-3169 (2018)
link
44
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Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions
Hochberg GKA, Shepherd DA, Marklund EG, Santhanagoplan I, Degiacomi MT, Laganowsky A, Allison TM, Basha E, Marty M, Galpin MR, Struew WB, Baldwin AJ, Vierling E, Benesch LP
Science 359, 6378 930 2018
link
pdf
Hochberg GKA, Shepherd DA, Marklund EG, Santhanagoplan I, Degiacomi MT, Laganowsky A, Allison TM, Basha E, Marty M, Galpin MR, Struew WB, Baldwin AJ, Vierling E, Benesch LP
Science 359, 6378 930 2018
link
43
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Selective radical trifluoromethylation of native residues in proteins
Imiołek M, Karunanithy G, Ng WL, Baldwin AJ, Gouverneur VE, Davis BG
JACS 140(5) 1568 2018
link
Imiołek M, Karunanithy G, Ng WL, Baldwin AJ, Gouverneur VE, Davis BG
JACS 140(5) 1568 2018
link
42
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Structural and hydrodynamic properties of intrinsically disordered Ddx4 molecules upon phase separation
Brady J, Farber PJ, Shekhar A, Lin Y-H, Huang R, Bah A, Nott TJ, Chan HS, Baldwin AJ, Forman-Kay J, Kay LE
PNAS 114(39) 2017
link
Brady J, Farber PJ, Shekhar A, Lin Y-H, Huang R, Bah A, Nott TJ, Chan HS, Baldwin AJ, Forman-Kay J, Kay LE
PNAS 114(39) 2017
link
41
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40
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Proline isomerization in the C-terminal region of HSP27
Alderson R, Benesch JLP, Baldwin AJ,
Cell and cell stress 22(4):639-651 2017
Alderson R, Benesch JLP, Baldwin AJ,
Cell and cell stress 22(4):639-651 2017
39
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38
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Monitoring the disassembly of virus-like particles by 19F-NMR
Leung RLC, Robinson MDM, Alaa AAA, Karunanithy G, Lyons B, Raj R, Raoufmoghaddam S, Mohammed S, Claridge TDW, Baldwin AJ, Davis BG
J. Am. Chem. Soc. (2017) 139 5277
link
37
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The role of interfacial lipids in stabilising membrane protein oligomers
Gupta K, Donlan JAC, Hopper JTS, Uzdavinys P, Landreh M, Struwe WB, Drew D, Baldwin AJ, Stansfeld PJ, Robinson CV
Nature (2017) 541, 421–424
link
36
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Post-translational mutagenesis: a chemical strategy for exploring protein side-chain diversity
Wright TH, Bower BJ, Chalker JM, Bernardes GJL, Wiewiora R, Ng WL, Raj R, Faulkner S, Vallée MRJ, Phanumartwiwath A, Coleman OD, Thézénas ML, Khan M, Galan SRG, Lercher L, Schombs MW, Gerstberger S, Palm-Espling MEP, Baldwin AJ, Kessler BM, Claridge TDW, Mohammed S, Davis BG
Science (2016) 354, 596 and aag1465 2016
Featured in a Perspective in Science, a Research Highlight in Nature Methods and in an Article in Chemical & Engineering News.
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Determination of an optimally sensitive and specific Chemical Exchange Saturation Transfer MRI quantification metric in relevant biological phantoms
Ray KJ, Larkin JR, Tee YK, Khrapitchev AA, Karunanithy G, Barber M, Baldwin AJ, Chappell MA, Sibson NR
NMR in biomedicine (2016) 29 (11), 1624-1633
pdf
supp
Ray KJ, Larkin JR, Tee YK, Khrapitchev AA, Karunanithy G, Barber M, Baldwin AJ, Chappell MA, Sibson NR
NMR in biomedicine (2016) 29 (11), 1624-1633
supp
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33
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32
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Quantifying the stabilizing effects of protein-ligand interactions in the gas phase
Allison TM, Reading E, Liko I, Baldwin AJ, Laganowsky A, Robinson CV
Nature Communications (2015) DOI: 10.1038/ncomms9551
31
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Investigating the Mechanisms of Amylolysis of Starch Granules by Solution-State NMR
Baldwin AJ, Egan D, Warren F, Barker PD, Dobson CM, Butterworth P, Ellis P
Biomacromolecules (2015) 16, 1614−1621
30
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Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles
Marty MT, Baldwin AJ, Marklund EG, Hochberg GKA, Benesch JLP, Robinson CV
Anal. Chem. (2015) 87 (8) 4370-4376
29
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Collision Cross Sections for Structural Proteomics
Markland EG, Degiacomi MT, Robinson CV, Baldwin AJ, Benesch JLP
Structure (2015) 23(4):791-9
28
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Combining tandem mass spectrometry with ion mobility separation to determine the architecture of polydisperse proteins
Shepherd DA, Marty MT, Giles K, Baldwin AJ, Benesch JLP
Int. J mass spec. (2015) 377(1)
pdf
Shepherd DA, Marty MT, Giles K, Baldwin AJ, Benesch JLP
Int. J mass spec. (2015) 377(1)
27
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26
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Membrane proteins bind lipids selectively to modulate their structure and function
Laganowsky A, Reading E, Allison T, Ulmschneider MB, Degiacomi MT, Baldwin AJ, Robinson CV
Nature (2014), 510 7503, 172-175
link
Laganowsky A, Reading E, Allison T, Ulmschneider MB, Degiacomi MT, Baldwin AJ, Robinson CV
Nature (2014), 510 7503, 172-175
link
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The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity
Hochberg GKA, Ecroyd H, Liu C, Cox D, Csciod D, Sawaya MR, Colliera MP, Stroud J, Carver JA, Baldwin AJ, Robinson CV, Eisenberg DS, Benesch JLP, Laganowsky A
PNAS (2014) 111, E1562-70
pdf
supp
commentary
Hochberg GKA, Ecroyd H, Liu C, Cox D, Csciod D, Sawaya MR, Colliera MP, Stroud J, Carver JA, Baldwin AJ, Robinson CV, Eisenberg DS, Benesch JLP, Laganowsky A
PNAS (2014) 111, E1562-70
supp
commentary
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An R1ρ expression for a spin in chemical exchange between two sites with unequal transverse relaxation rates
Baldwin AJ, Kay LE
J. Biol. NMR (2013), 55:211-218
pdf
Baldwin AJ, Kay LE
J. Biol. NMR (2013), 55:211-218
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21
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Small heat-Shock proteins: paramedics of the cell
Hilton GR, Lioe H, Stengel F, Baldwin AJ, Benesch JLP
Top. Curr. Chem. (2013) 328:69-98
pdf
Hilton GR, Lioe H, Stengel F, Baldwin AJ, Benesch JLP
Top. Curr. Chem. (2013) 328:69-98
20
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Twisting Transition between Crystalline and Fibrillar Phases of Aggregated Peptides
Knowles TPJ, Simone AD, Fitzpatrick AW, Baldwin AJ, Meehan S, Rajah L, Vendruscolo M, Welland ME, Dobson CM, Terentjev EM
PRL (2012) 109(15) 15101
pdf
Knowles TPJ, Simone AD, Fitzpatrick AW, Baldwin AJ, Meehan S, Rajah L, Vendruscolo M, Welland ME, Dobson CM, Terentjev EM
PRL (2012) 109(15) 15101
18
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Dissecting heterogeneous molecular chaperone complexes using a mass spectrum deconvolution approach
Baldwin AJ*, Stengel F*, Bush MF, Hilton GR, Lioe H, Basha E, Jaya N, Vierling E, Benesch JLP
Chem & Biol. (2012) 19: 599-607
pdf
supp
commentary Slingsby C, Clark AR
Baldwin AJ*, Stengel F*, Bush MF, Hilton GR, Lioe H, Basha E, Jaya N, Vierling E, Benesch JLP
Chem & Biol. (2012) 19: 599-607
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commentary Slingsby C, Clark AR
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Measurement of the signs of methyl chemical shift differences between ground and excited protein states by R1ρ: an application to αB-crystallin
Baldwin AJ, Kay LE
J. Biol. NMR (2012) 53(1): 1
pdf
Baldwin AJ, Kay LE
J. Biol. NMR (2012) 53(1): 1
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Quaternary dynamics of αB-crystallin as a direct consequence of localised tertiary fluctuations in the C-terminus
Baldwin AJ, Hilton GR, Lioe H, Bagnéris C, Benesch JLP, Kay LE
J. Mol. Biol. (2011) 413: 310-20
pdf
supp
commentary Carver JA
Baldwin AJ, Hilton GR, Lioe H, Bagnéris C, Benesch JLP, Kay LE
J. Mol. Biol. (2011) 413: 310-20
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commentary Carver JA
12
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αB-crystallin polydispersity is a consequence of unbiased quaternary dynamics
Baldwin AJ, Lioe H, Robinson CV, Kay LE, Benesch JLP
J. Mol. Biol. (2011) 413: 297-309
pdf
supp
commentary Carver JA
Baldwin AJ, Lioe H, Robinson CV, Kay LE, Benesch JLP
J. Mol. Biol. (2011) 413: 297-309
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commentary Carver JA
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Filed in:Research Articles
Metastability of native proteins towards amyloid formation
Baldwin AJ, Knowles TPJ, Devlin GL, Shammas SL, Fitzpatrick AW, Waudby C, Mossuto MF, Meehan S, Gras SL, Christodoulou J, Anthony-Cahill SJ, Barker PD, Vendruscolo M, Dobson CM
JACS (2011) 133: 14160-14163
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commentary Thirumalai D, Reddy G, Nature Chemistry
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Filed in:Research Articles
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Filed in:Research Articles
The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated
Benesch JLP, Aquilina JA, Baldwin AJ, Rekas A, Stengel F, Lindner R, Basha E, Devlin G, Horwitz J, Vierling E, Carver JA, Robinson CV
Chem. Biol. (2010) 17: 1008-17
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Filed in:Research Articles
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Filed in:Research Articles
Quaternary dynamics and plasticity underlie small heat shock protein chaperone function
Stengel, F, Baldwin, AJ, Painter AJ, Jaya N, Basha E, Kay LE, Vierling E, Robinson CV, Benesch JLP
Proc. Natl. Acad. Sci. U.S.A. (2010), 107: 2007-12
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commentary, Eyles S, Gierasch LM
Stengel, F, Baldwin, AJ, Painter AJ, Jaya N, Basha E, Kay LE, Vierling E, Robinson CV, Benesch JLP
Proc. Natl. Acad. Sci. U.S.A. (2010), 107: 2007-12
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commentary, Eyles S, Gierasch LM
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Filed in:Reviews
NMR spectroscopy brings invisible protein states into focus
Baldwin AJ, Kay LE
Nature Chemical Biology (2009) 5: 808-814
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Baldwin AJ, Kay LE
Nature Chemical Biology (2009) 5: 808-814
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Filed in:Research Articles
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Characterisation of amyloid fibril formation by the small heat-shock protein αB-crystallin and manipulation of the protofilament substructure
Meehan S, Knowles TPJ, Baldwin AJ, Smith J, Squires AM, Clements P, Treweek TM, Ecroyd H, Tartaglia GG, Vendruscolo M, MacPhee CM, Dobson CM, Carver JA
J Mol. Biol. (2007) 372: 470-484
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Meehan S, Knowles TPJ, Baldwin AJ, Smith J, Squires AM, Clements P, Treweek TM, Ecroyd H, Tartaglia GG, Vendruscolo M, MacPhee CM, Dobson CM, Carver JA
J Mol. Biol. (2007) 372: 470-484
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Contribution of rotational diffusion to PFGSE measurements
Baldwin AJ, Christodoulou J, Dobson CM, Lippens G.
J. Chem. Phys. (2007) 127: 114505-8
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Baldwin AJ, Christodoulou J, Dobson CM, Lippens G.
J. Chem. Phys. (2007) 127: 114505-8
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