Used to analyze 1D electrospray mass spectra where a protein M is binding a ligand P giving complexes with stoichiometries of the form MiPj. The program assumes that the concentrations of the various complexes can be described by a continuous distribution function. We applied this approach in studies of clients binding to sHSP oligomers.

Dissecting heterogeneous molecular chaperone complexes using a mass spectrum deconvolution approach
Stengel F, Baldwin AJ, Bush MF, Hilton GR, Lioe H, Basha E, Jaya N, Vierling E, Benesch JLP
Chem & Biol. (2012), 19, 599-607
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commentary Slingsby C, Clark AR