Tim Nott

Tim obtained a PhD in structural biology at the National Institute for Medical Research (NIMR) in the UK, before moving to the Pawson Lab in Toronto, Canada, to pursue a postdoc in cell biology. Here, he studied how living cells are internally compartmentalised, and in particular how phase separation gives rise to liquid droplet-like membraneless organelles and compartments. In the Baldwin Lab, Tim is continuing his research on this theme, focussing on how the internal membraneless organelle environment influences biochemical reactions.
Tim was a Todd-Bird Junior Research Fellow at New College, Oxford.
Tim now runs a group in biochemistry in Oxford, funded by a Henry-Dale Wellcome/RSC fellowship.

timothy.nott AT chem.ox.ac.uk

Henrik Müller

Research interests
Fatal neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and prion diseases (e.g. mad cow disease) share a common cause. Cellular proteins that, under normal circumstances have a functional role in the body, distort and form long amyloid fibrils, which are non-crystalline and heterogeneous, and can even be infectious. Henrik is interested in understanding (i) the structural details of how benign proteins are converted into causative agents of deadly diseases and (ii) the molecular mechanism by which the human defensive system, in the form of chaperoning small heat shock proteins, inhibits the formation of those protein fibrils.

His work involves an inter-disciplinary combination of biophysical techniques such as electron microscopy (EM), atomic force microscopy (AFM), circular dichroism (CD) spectroscopy, differential ultracentrifugation, ion-mobility mass spectrometry (IMS), and chromatographic techniques with cell and animal-based toxicity assays and cutting edge high-molecular weight solution-state and solid-state NMR spectroscopy.

University and college roles and committees
Postdoctoral Research Associate, Department of Chemistry
Junior Research Fellow at Pembroke College
MPLS representative of the Oxford Research Staff Society (OxRSS)


henrik.muller AT chem.ox.ac.uk

Mike Barber

Michael completed a biological sciences degree at the University of Leeds and is now enrolled on the interdisciplinary bioscience doctoral training partnership. Michael studies the structure and dynamics of RNA regulatory enzymes and Gaucher's disease associated Glucocerebrosidase.

Mike graduated in September 2016 and now worked in aid and development in Africa.

michael.barber AT biodtp.ox.ac.uk

Iva Pritišanac

Iva studied Molecular Biology (B.S.) at the University of Zagreb, Croatia, and subsequently moved to the University of Utrecht, the Netherlands, where she graduated in Molecular and Cellular Life Sciences (M.S.). During her master studies Iva focused on structural biology, performing her major and minor research projects in NMR spectroscopy and X-ray crystallography, respectively. Iva's master's thesis focused on the usefulness of distance restraints derived from EPR and sm-FRET spectroscopic techniques as applied to the computational docking of protein-protein and protein-nucleic acid complexes with HADDOCK. Her interest in using restraints from experimental techniques in computational structural biology continues in her PhD research, which focuses on using experimental restraints from solution-state NMR spectroscopy to automate resonance assignment in spectra of high molecular weight proteins.

Iva graduated in December 2016 and now worked in Frankfurt with Prof. Peter Guntert.


iva.pritisanac AT magd.ox.ac.uk

Olga Tkachenko

Olga studied Natural Sciences (Biochemistry) at the University of Cambridge as a member of St. Catharine's College, and spent a year as an exchange student at the University of Heidelberg. She is now a DPhil student and a Lamb and Flag Scholar at St John's College. Olga is interested in conformational dynamics of proteins and in combining advanced biophysical methods to study them, and is supervised jointly by Andrew and by Justin Benesch.


olga.tkachenko AT sjc.ox.ac.uk