2014

David Miguel Dias

David obtained his MSc. in Biochemistry at the University of Coimbra (Portugal). In 2011, he was awarded a PhD fellowship from the Portuguese Foundation for Science and Technology (FCT) to join the Ciulli and Abell laboratories in Cambridge (UK). Here he focused on targetting protein-protein interaction (PPIs) via fragment-based lead discovery approaches. David's work involves a wide set of bophysical methods but he has been mainly using NMR spectroscopy as a tool to screen and structurally validate fragment binding against several targets. David had joined the Baldwin group to explore the relationship between drug discovery and protein dynamics. He is interested in understanding how mechanisms of proteins aggregation in amyloid diseases can be better understood and potentially use that insight as a rationale for hit generation against amyloid-like proteins.

Publications

CONTACT INFORMATION:
david.dias AT chem.ox.ac.uk

Reid Alderson


Reid studied Biochemistry (B.S.) at the University of Wisconsin-Madison, and is now a Ph.D. student in the National Institutes of Health (NIH) Oxford-Cambridge Scholars Program, in which he was also supervised by Ad Bax and Justin Benesch. Alongside other biophysical tools, Reid studied the structure, dynamics, and function of biomolecules with NMR spectroscopy and native mass spectrometry.

Publications

CONTACT INFORMATION:
reid.alderson AT pmb.ox.ac.uk

Magdeline Ira-Nathan